高雄

个人简历
一、教育经历: 
2007.09—2011.07, 福建农林大学食品科学学院食品科学与工程专业,本科 ; 
2011.09—2017.12, 华南农业大学食品学院食品科学专业,硕博连读 ; 
2016.07—2017.07, 美国Rutgers大学食品科学系,交流访学 。 
二、工作经历: 
2018.07—至今,广东省科学院微生物研究所,助理研究员
研究领域
主要致力于食药用菌多糖提取、分离纯化、结构鉴定及其生物活性的研究,主要包括免疫调节、抗氧化、抗肿瘤等方面。
社会任职
代表性发表论著、论文和专利
一、论文: 
1.Xiong Gao, Ranhua Zeng, Jiayi Qi, Chi-Tang Ho, Bin Li, Zhongzheng Chen, Shaodan Chen, Chun Xiao, Huiping Hu, Manjun Cai, Yizhen Xie*, Qingping Wu*. Immunoregulatory activity of a low-molecular-weight heteropolysaccharide from Ganoderma leucocontextum fruiting bodies in vitro and in vivo. Food Chemistry: X, 2022, 14: 100321. 
2.Xiong Gao, Ranhua Zeng, Chi-Tang Ho, Bin Li, Shaodan Chen, Chun Xiao, Huiping Hu, Manjun Cai, Zhongzheng Chen, Yizhen Xie*, Qingping Wu*. Preparation, chemical structure, and immunostimulatory activity of a water-soluble heteropolysaccharide from Suillus granulatus fruiting bodies. Food Chemistry: X, 2022, 13: 100211. 
3.Xiong Gao, Jiayi Qi, Chi-Tang Ho, Bin Li, Yizhen Xie, Shaodan Chen, Huiping Hu, Zhongzheng Chen*, Qingping Wu*. Purification, physicochemical properties, and antioxidant activities of two low-molecular-weight polysaccharides from Ganoderma leucocontextum fruiting bodies. Antioxidants, 2021, 10: 1145. 
4.Xiong Gao, Jiayi Qi, Chi-Tang Ho, Bin Li, Jingjing Mu, Yuting Zhang, Huiping Hu, Weipeng Mo, Zhongzheng Chen*, Yizhen Xie*. Structural characterization and immunomodulatory activity of a water-soluble polysaccharide from Ganoderma leucocontextum fruiting bodies. Carbohydrate Polymers, 2020, 249: 116874. 
5.Xiong Gao, Xiaofei Li, Jingjing Mu, Chi-Tang Ho, Jiyan Su, Yuting Zhang, Xiaorong Lin, Zhongzheng Chen, Bin Li*, Yizhen Xie*. Preparation, physicochemical characterization, and anti-proliferation of selenium nanoparticles stabilized by Polyporus umbellatus polysaccharide. International Journal of Biological Macromolecules, 2020, 152: 605-615. 
二、授权专利: 
1.高雄; 吴清平; 谢意珍; 穆静静; 胡惠萍; 莫伟鹏. 具有抗氧化功效的西藏灵芝多糖GLP-1、制备方法与应用,ZL202011000300.1. 
2.高雄; 穆静静; 谢意珍; 胡惠萍; 莫伟鹏. 西藏灵芝多糖GLP-3及其制备方法与应用, ZL202010267013.0.
荣誉奖励
主持项目(省部级以上)
1.广东省区域联合基金-青年基金项目,灵芝多糖-纳米硒基于铁死亡途径调控GPx4减缓肝脏氧化损伤的研究, 2020.01-2022.06; 
2.广东省自然科学基金-面上项目,灵芝多糖通过TLR2、Dectin-1受体调控M2型巨噬细胞向M1型极化抗结肠癌的机制研究,2013.01-2015.12

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