董义杰

个人简历
2019.09至今         广东省科学院微生物研究所,助理研究员 
2016.09-2019.09   中国农业科学院植物保护研究,博士后 
2013.09-2016.07   南开大学,理学博士 
2011.09-2013.07   清华大学,科研助理 
2008.09-2011.07   黑龙江大学,理学硕士 
2006.09-2008.07   黑龙江大学,理学学士
研究领域
黏细菌关键基因的功能研究;细菌竞争机制的研究;多重耐药菌防控策略的研究
代表性发表论著、论文和专利
1. Dong Yijie, Li Xiaohui, Duan Jiaqi, Qin Youcai, Yang Xiufen, Ren Jie and Li Guangyue*. Improving the Yield of Xenocoumacin 1 Enabled by In Situ Product Removal. ACS Omega 2020, 5: 20391-20398. 
2. Li Guangyue, Dong Yijie, and Manfred T. Reetz*. Can Machine Learning Revolutionize Directed Evolution of Selective Enzymes? Adv. Synth. Catal 2019, 361, 2377-2386. 
3. Dong Yijie, Yao Peiyuan (Co-first author), Cui Yunfeng, Wu Qiaqing, Zhu Dunming*, Li Guangyue* and Manfred T. Reetz*. Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols. Biological chemistry, 2019, 400.3: 313-321. 
4. Yang Yuankun, Yang Xiufen, Dong Yijie* (Corresponding author), Qiu Dewen*, The Botrytis cinerea xylanase BcXyl1 modulates plant immunity, Frontiers in Microbiology 2018, 9. 
5. Yuankun Yang, Yi Zhang, Beibei Li, Xiufen Yang, Yijie Dong* (Corresponding author), Dewen Qiu*, A Verticillium dahliae Pectate Lyase Induces Plant Immune Responses and Contributes to Virulence, Frontiers in Plant Science, 2018, 9: 1271. 
6. Dong Yijie, Zhang Dan, Yu Qilin, Zhao Qiang, Xiao Chenpeng, Zhang Kai, Jia Chang, Chen Sijia, Zhang Bing, Zhang Biao and Li Mingchun*. Loss of Ssq1 leads to mitochondrial dysfunction, activation of autophagy and cell cycle arrest due to iron overload triggered by mitochondrial iron-sulfur cluster assembly defects in Candida albicans. International Journal of Biochemistry & Cell Biology 2017, 85: 44-55. 
7. Dong Yijie, Yu Qilin, Chen Yulu, Xu Ning, Zhao Qiang, Jia Chang, Zhang Bing, Zhang Kai, Zhang Biao, Xing Laijun and Li Mingchun*. The Ccz1 mediates the autophagic clearance of damaged mitochondria in response to oxidative stress in Candida albicans. International Journal of Biochemistry & Cell Biology 2015, 69: 41-51. 
8. Dong Yijie, Lang Zhe, Kong Xian, Lu Diannan, Liu Zheng*. Kinetic and multidimensional profiling of accelerated degradation of oil sludge by biostimulation. Environmental Science Processes & Impacts 2015, 17(4): 763. 
9. Xu Ning, Dong Yijie (Co-first author), Yu Qilin, Zhang Bing, Zhang Meng, Jia Chang Chen Yulu, Zhang Biao, Xing Laijun and Li Mingchun*. Convergent Regulation of Candida albicans Aft2 and Czf1 in Invasive and Opaque Filamentation. Journal of Cellular Biochemistry 2015, 116(9): 1908-1918. 
10. Yu Qilin, Dong Yijie (Co-first author), Xu Ning, Qian Kefan, Chen Yulu, Zhang Biao, Xing Laijun and Li Mingchun*. A novel role of the ferric reductase Cfl1 in cell wall integrity, mitochondrial function, and invasion to host cells in Candida albicans. Fems Yeast Research 2014, 14(7): 1037-1047.
主持项目(省部级以上)
1. 广东省自然科学基金-面上项目,2021A1515011143,铁摄取系统参与粘细菌捕食的分子机制研究,2021/01-2023/12,10万,在研,主持。 
2. 广东省科学院建设国内一流研究机构行动专项资金项目,2021GDASYL-20210103016,ABC转运体蛋白在粘细菌捕食过程的功能研究,2021/01-2023/12,54万,在研,主持。 
3. 国家自然科学基金青年基金项目,31701782,蛋白激发子Hrip1诱导番茄抗黄化曲叶病毒的互作蛋白鉴定与调控机制研究,2018/01-2020/12,24万,结题,主持。 
4. 中国博士后科学基金,2016M601189,水稻中与激发子MoHrip2互作蛋白的鉴定及其功能研究,2016/09-2018/06,5.0万元,结题,主持。

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